Ultrafast and accurate sequence alignment and clustering of viral genomes

Prelegent(ci)

Sebastian Deorowicz

Afiliacja

Silesian University of Technology

Język referatu

angielski

Termin

26 marca 2025 10:15

Pokój

p. 3250

Seminarium

Seminarium „Biologia obliczeniowa i bioinformatyka”

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Viromics produces millions of viral genomes and fragments annually, overwhelming traditional sequence comparison methods. We introduce Vclust, an approach that determines average nucleotide identity by Lempel-Ziv parsing and clusters viral genomes with thresholds endorsed by authoritative viral genomics and taxonomy consortia. Vclust demonstrates superior accuracy and efficiency compared to existing tools, clustering millions of genomes in a few hours on a mid-range workstation.

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